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A large number of anti-tumor drugs damage DNA and promote apoptosis to kill cancer cells [3]

Skipping Cycling Protocols The Problem: Continuous daily use without planned off-periods, assuming "more is better." Why It Matters: Prolonged use without breaks may lead to receptor desensitization, reduced effectiveness, and potential unknown long-term effects

During the evolution of Cyanobacteria and Proteobacteria, GSH-dependent ROS detoxification systems incorporated enzymes that play crucial roles in these mechanisms and use GSH as a cofactor, such as GSH peroxidases, GSH reductases, glutaredoxins, and GSH-S-transferases [41]

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